A700-022-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
IHC-IF
WB
mIF
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- residues 19-247 (mature protein)
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Granzyme B
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- C11, cathepsin G-like 1, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTLA-1, CTSGL1, cytotoxic serine protease B, cytotoxic T-lymphocyte proteinase 2, fragmentin 2, Fragmentin-2, granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), Granzyme-2, HLP, human lymphocyte protein, Lymphocyte protease, SECT, T-cell serine protease 1-3E
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1000
- Immunohistochemistry (IHC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Target Sentence
- Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
- Product Link
- http://www.bethyl.com/product/A700-022