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Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]

Catalog No.
A700-022-T
Pack Size
  • 10 µl (5+ tests)
  • 100 µl (50+ tests)
Quantity
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Brand:
Specifications
A700-022-T
Brand
Bethyl Laboratories
Application
ICC
IHC
IHC-IF
WB
mIF
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
residues 19-247 (mature protein)
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
Granzyme B
Shelf Life
1 year from date of receipt
Antibody Type
Recombinant Monoclonal
Alternate Names
C11, cathepsin G-like 1, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTLA-1, CTSGL1, cytotoxic serine protease B, cytotoxic T-lymphocyte proteinase 2, fragmentin 2, Fragmentin-2, granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), Granzyme-2, HLP, human lymphocyte protein, Lymphocyte protease, SECT, T-cell serine protease 1-3E
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:1000
Immunohistochemistry (IHC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Immunocytochemistry (ICC)
1:100 - 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
Immunohistochemistry-Immunofluoresence (IHC-IF)
1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
Target Sentence
Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]
Product Link
http://www.bethyl.com/product/A700-022
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