IHC-00274-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 650 and 700
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- GTF2IRD/TFII-IRD1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- BEN, binding factor for early enhancer, CREAM1, general transcription factor 3, general transcription factor III, general transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, GTF3, hMusTRD1alpha1, Muscle TFII-I repeat domain-containing protein 1, muscle TFII-I repeat domain-containing protein 1 alpha 1, MUSTRD1, MusTRD1/BEN, RBAP2, slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, WBS, WBSCR11, WBSCR12, Williams-Beuren syndrome chromosomal region 11 protein, williams-Beuren syndrome chromosomal region 12 protein, Williams-Beuren syndrome chromosome region 11
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- GTF2IRD1/TFII-IRD1 possesses five helix-loop-helix GTF2I-like repeats and has been shown to bind the GUCE (GTF2IRD1 upstream response element) regulatory motif found in HOXC8, GOOSECOID, and TROPONININ (SLOW) genes. GTF2IRD1/TFII-IRD1 may be involved in skeletal muscle differentiation and myogenesis. Haploinsufficiency of GTF2IRD1/TFII-IRD1 results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.
- Product Link
- http://www.bethyl.com/product/IHC-00274-T