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Rabbit anti-GTF2IRD/TFII-IRD1 IHC Antibody, Affinity Purified

Catalog No.
IHC-00274-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00274-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 650 and 700
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
GTF2IRD/TFII-IRD1
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
BEN, binding factor for early enhancer, CREAM1, general transcription factor 3, general transcription factor III, general transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, GTF3, hMusTRD1alpha1, Muscle TFII-I repeat domain-containing protein 1, muscle TFII-I repeat domain-containing protein 1 alpha 1, MUSTRD1, MusTRD1/BEN, RBAP2, slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, WBS, WBSCR11, WBSCR12, Williams-Beuren syndrome chromosomal region 11 protein, williams-Beuren syndrome chromosomal region 12 protein, Williams-Beuren syndrome chromosome region 11
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
GTF2IRD1/TFII-IRD1 possesses five helix-loop-helix GTF2I-like repeats and has been shown to bind the GUCE (GTF2IRD1 upstream response element) regulatory motif found in HOXC8, GOOSECOID, and TROPONININ (SLOW) genes. GTF2IRD1/TFII-IRD1 may be involved in skeletal muscle differentiation and myogenesis. Haploinsufficiency of GTF2IRD1/TFII-IRD1 results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.
Product Link
http://www.bethyl.com/product/IHC-00274-T
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