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Rabbit anti-hPrp3p IHC Antibody, Affinity Purified

Catalog No.
IHC-00516-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00516-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 100 and 150
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
hPrp3p
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
HPRP3, HPRP3P, pre-mRNA-splicing factor 3, PRP3, PRP3 pre-mRNA processing factor 3 homolog, Prp3p, RP18, SNRNP90, U4/U6 small nuclear ribonucleoprotein Prp3, U4/U6 snRNP 90 kDa protein, U4/U6-associated RNA splicing factor
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
hPrp3p (human pre-mRNA splicing factor 3) was identified as a factor that associated with U4/U6 snRNPs which are components of the splicesome. hPrp3p is homologous to S. cerevisiae splicing factor Prp3p. Mutations in the PRPF3 gene are associated with retinitis pigmentosa-18. It has been determined that mutations in hPrp3p may alter the recognition motif for phosphorylation by casein kinase II (CKII) and that loss of phosphorylation may result in aberrant interactions within the U4/U6 snRNP complex.
Product Link
http://www.bethyl.com/product/IHC-00516-T
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