Rabbit anti-HURP/DLG7 IHC Antibody, Affinity Purified
Brand:
IHC-00170-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 200 and 250
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- HURP/DLG7
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- DAP-5, Discs large homolog 7, discs large homolog associated protein 5, discs, large homolog 7, disks large-associated protein 5, disks large-associated protein DLG7, DLG7, hepatoma up-regulated protein, HURP
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- HURP/DLG7 (Hepatoma Up-Regulated Protein/Disks Large Homolog 7) is a member of the MAGUK (membrane-associated guanylate kinase) family of scaffolding proteins. There are seven DLG homologs in mammals that play important roles in regulating proliferation, epithelial cell polarity, cell adhesion, and synapse formation. HURP/DLG7 has been identified as a microtubule-associated protein (MAP) that colocalizes with the mitotic spindle and functions as a mitotic regulator. HURP/DLG7 is required for microtubule attachment and efficient capture of kinetochores, as well as timely chromosome congression. HURP/DLG7 is up-regulated in human cancer cells and may contribute to tumorigenesis.
- Product Link
- http://www.bethyl.com/product/IHC-00170
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