Rabbit anti-IDE Antibody, Affinity Purified
Brand:
A301-906A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 275 and 326
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- IDE
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Abeta-degrading protease, insulin protease, insulinase, insulin-degrading enzyme, INSULYSIN
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Insulin-degrading enzyme (IDE) is a metalloendopeptidase that plays a primary role in the regulated degradation of insulin. In the cell, IDE is found mostly in the soluble cytosolic fraction, and small amounts exist in the plasma membrane, endosomes, and peroxisomes; however the highest relative concentration is found in the peroxisomes. IDE is proposed to be a multifunctional enzyme since it is also present in non-insulin sensitive cells. Other substrates of IDE include glucagon, IGF-II, atrial natriuretic factor, and TGF-alpha.
- Product Link
- http://www.bethyl.com/product/A301-906A
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