A301-258A-M
- Brand
- Bethyl Laboratories
- Application
- ICC-IF
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 402 and 451
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- ILK
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 59 kDa serine/threonine-protein kinase, epididymis secretory protein Li 28, HEL-S-28, ILK-1, ILK-2, integrin-linked kinase-2, integrin-linked protein kinase, P59, p59ILK
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Guinea pig_10141 and Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunocytochemistry-Immunofluoresence (ICC-IF)
- 1:100 - 1:500. Acetone fixation is recommended. Permeabilization is not recommended. Formaldehyde fixation is not recommended.
- Target Sentence
- Integrin-linked kinase (ILK) is a serine/threonine kinase associated with the cytoplasmic domain of beta integrins and mediates integrin signaling from the extracellular matrix to the intracellular actin cytoskeleton. PKB/Akt and GSK-3beta are targets of ILK involved in integrin-mediated cell proliferation and cell survival. ILK has been shown to interact with Paxillin, PINCH-1, PINCH-2, and parvin to influence actin dynamics.
- Product Link
- http://www.bethyl.com/product/A301-258A