Rabbit anti-INPPL1/SHIP2 Antibody, Affinity Purified
Brand:
A300-574A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 100 and 150
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- INPPL1/SHIP2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 51C protein, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, OPSMD, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, protein 51C, SH2 domain-containing inositol 5'-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SH2 domain-containing inositol-5'-phosphatase 2, SHIP2, SHIP-2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
- Target Sentence
- INPPL1 (Inositol Polyphosphate Phosphatase-Like Protein 1) is a phosphatidylinositol phosphatase that negatively regulates phosphoinositide 3-kinase (PI3K) pathways related to numerous cell activities. INPPL1 plays a role in PI3K-dependent insulin, macrophage colony-stimulating factor, and EGF signaling. INPPL1 is also involved in actin cytoskeletal remodeling, actin dynamics, and neuritogenesis. INPPL1 interacts with SHC1 (src-homology domain) to mediate EGFR signaling.
- Product Link
- http://www.bethyl.com/product/A300-574A
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