Rabbit anti-IQCB1 Antibody, Affinity Purified
Brand:
A305-499A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 548 and 598
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- IQCB1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- IQ calmodulin-binding motif-containing protein 1, nephrocystin 5, Nephrocystin-5, NPHP5, p53 and DNA damage-regulated IQ motif protein, PIQ, SLSN5
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-499A has not performed satisfactorily when used for WB of IQCB1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of IQCB1.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- IQ calmodulin-binding motif-containing protein 1 (IQCB1) is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQCB1 has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQCB1 is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5 [taken from NCBI Entrez Gene (Gene ID: 9657)].
- Product Link
- http://www.bethyl.com/product/A305-499A
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