A304-270A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 675 and 725
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- LMTK2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- AATYK2, apoptosis-associated tyrosine kinase 2, brain-enriched kinase, BREK, CDK5/p35-regulated kinase, cprk, cyclin-dependent kinase 5/p35-regulated kinase, hBREK, kinase/phosphatase/inhibitor 2, KPI2, KPI-2, Lemur tyrosine kinase 2, LMR2, PPP1R100, protein phosphatase 1, regulatory subunit 100, serine/threonine-protein kinase KPI-2, serine/threonine-protein kinase LMTK2
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].
- Product Link
- http://www.bethyl.com/product/A304-270A