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Rabbit anti-MED15 IHC Antibody, Affinity Purified

Catalog No.
IHC-00680-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00680-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 450 and 500
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
MED15
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
activator-recruited cofactor 105 kDa component, activator-recruited cofactor, 105-kD, ARC105, CAG7A, CTG repeat protein 7a, CTG7A, Mediator complex subunit 15, mediator of RNA polymerase II transcription subunit 15, PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, PC2-glutamine-rich-associated protein, PCQAP, Positive cofactor 2 glutamine/Q-rich-associated protein, positive cofactor 2, glutamine/Q-rich-associated protein, TIG1, TIG-1, TNRC7, TPA inducible gene-1, TPA inducible protein, TPA-inducible gene 1 protein, trinucleotide repeat containing 7, trinucleotide repeat-containing gene 7 protein
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
Mediator complex subunit 15 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. MED15 is required for cholesterol-dependent gene regulation. It also positively regulates the Nodal signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96RN5].
Product Link
http://www.bethyl.com/product/IHC-00680-T
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