Rabbit anti-MKK4 Antibody, Affinity Purified
Brand:
A302-657A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 50 and 100
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- MKK4
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- c-Jun N-terminal kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 4, JNK-activated kinase 1, JNK-activating kinase 1, JNKK, JNKK1, MAP kinase kinase 4, MAPK/ERK kinase 4, MAPKK 4, MAPKK4, MEK 4, MEK4, MKK4, PRKMK4, SAPK kinase 1, SAPK/ERK kinase 1, SAPKK1, SAPKK-1, SEK1, SERK1, SKK1, stress-activated protein kinase kinase 1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. Use rabbit anti-MKK4 antibody A302-658A.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- MAPKK4 (mitogen-activated protein kinase kinase 4) is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. MAPKK4 is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. Studies in knockout mice suggest that MAPKK4 mediates survival signals in T cell development. It may also be important to liver organogenesis.[taken from NCBI Entrez Gene (GeneID: 6416)].
- Product Link
- http://www.bethyl.com/product/A302-657A
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