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Rabbit anti-MMS21 Antibody, Affinity Purified

Catalog No.
A304-129A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A304-129A-T
Brand
Bethyl Laboratories
Application
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 197 and 247
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
MMS21
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
C8orf36, E3 SUMO-protein ligase NSE2, E3 SUMO-protein transferase NSE2, hMMS21, methyl methanesulfonate sensitivity gene 21, MMS21, MMS21 homolog, Non-SMC element 2 homolog, non-SMC element 2, MMS21 homolog, non-structural maintenance of chromosomes element 2 homolog, NSE2, NSMCE2/PVT1 fusion, PVT1/NSMCE2 fusion, zinc finger, MIZ-type containing 7, ZMIZ7
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. A304-129A has not performed satisfactorily when used for WB of MMS21 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MMS21.
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Target Sentence
The human MMS21 (Methyl Methanesulfonate-Sensitivity protein 21) homolog is also known as E3 SUMO-protein ligase NSE2. MMS21 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand break repair by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96MF7].
Product Link
http://www.bethyl.com/product/A304-129A
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