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Rabbit anti-MSH2 Recombinant Monoclonal Antibody [BLR116H]
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Brand:
A700-116-T
- Brand
- Bethyl Laboratories
- Application
- ICC
IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 625 and 675
- Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- MSH2
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Recombinant Monoclonal
- Alternate Names
- COCA1, DNA mismatch repair protein Msh2, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, mutS homolog 2, colon cancer, nonpolyposis type 1, MutS protein homolog 2
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000
- Immunoprecipitation (IP)
- 20 µl/1 mg lysate
- Immunohistochemistry (IHC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.
- Immunocytochemistry (ICC)
- 1:100 to 1:500. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
- Target Sentence
- MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).
- Product Link
- http://www.bethyl.com/product/A700-116
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