Rabbit anti-mTOR Antibody, Affinity Purified
Brand:
A301-144A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1675 and 1725
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- mTOR
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FKBP-rapamycin associated protein, FRAP, FRAP1, FRAP2, mammalian target of rapamycin, Mechanistic target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), mTOR, RAFT1, rapamycin and FKBP12 target 1, rapamycin associated protein FRAP2, rapamycin target protein 1, RAPT1, serine/threonine-protein kinase mTOR, SKS
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt.
- Product Link
- http://www.bethyl.com/product/A301-144A
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