Rabbit anti-NECTIN1/CD111/PVRL1 Antibody, Affinity Purified
Brand:
A305-162A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 225 and 275
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- NECTIN1/CD111/PVRL1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CD antigen CD111, CD111, CLPED1, ectodermal dysplasia 4 (Margarita Island type), ED4, herpes simplex virus type 1 sensitivity, herpes virus entry mediator C, Herpesvirus entry mediator C, herpesvirus Ig-like receptor, HIgR, HV1S, HVEC, nectin 1, Nectin cell adhesion molecule 1, nectin-1, OFC7, poliovirus receptor-like 1, poliovirus receptor-related 1 (herpesvirus entry mediator C), poliovirus receptor-related protein 1, PRR, PRR1, PVRL1, PVRR, PVRR1, SK-12
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-162A has not performed satisfactorily when used for WB of NECTIN1/CD111/PVRL1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of NECTIN1/CD111/PVRL1.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- NECTIN1, also known as PVRL1, encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. This protein, Nectin-1 or CD111, is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily. Nectin-1 acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 , and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) [taken from NCBI Entrez Gene (Gene ID: 5818)].
- Product Link
- http://www.bethyl.com/product/A305-162A
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