A302-769A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 300 and 350
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- NFAT3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- NFAT3, NF-AT3, NFATc4, NF-ATC4, nuclear factor of activated T-cells, cytoplasmic 4, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4, T-cell transcription factor NFAT3
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- NFAT3 (nuclear factor of activated T-cells 3) plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. NFAT3 is transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. NFAT3 increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. It may also play an important role in myotube differentiation, cardiac development and hypertrophy, and in deafferentation-induced apoptosis of sensory neurons [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14934].
- Product Link
- http://www.bethyl.com/product/A302-769A