Rabbit anti-NUMB Antibody, Affinity Purified
Brand:
A301-714A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 375 and 425
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- NUMB
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- c14_5527, C14orf41, h-Numb, numb homolog, protein numb homolog, Protein S171, S171
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- NUMB plays an essential role in the determination of cell fate and development and appears to be especially important to sensory organogenesis and neurogenesis. NUMB is a notch1-interacting protein that antagonizes the notch1 signaling pathway. In the cell, NUMB is asymmetrically localized. The polarized distribution of NUMB in the cell is fundamental to its function of promoting asymmetric cell division for cell fate specification. Numb is also implicated to function as an endocytic protein, as it interacts with EPS15, a protein involved in endocytosis.
- Product Link
- http://www.bethyl.com/product/A301-714A
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