A301-795A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1837 and 1887
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- NUP210
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- GP210, nuclear envelope pore membrane protein POM 210, nuclear pore membrane glycoprotein 210, nuclear pore protein gp210, nucleoporin 210kDa, nucleoporin Nup210, POM210, pore membrane protein of 210 kDa
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- The nuclear pore complex (NPC) is a structure that spans the nuclear envelope and provides a conduit between the nucleus and cytoplasm for the nucleocytoplasmic transport of macromolecules. The main components of the NPC are nucleoporins. About 30 different human Nups have been identified and appear to serve non-redundant functions. Nup210 is a membrane-spanning glycoprotein and major component of the NPC. It is essential for nuclear envelope structure and cell viability. Autoantibodies to Nup210 have been observed in patients with primary biliary cirrhosis (PBC), an autoimmune liver disease.
- Product Link
- http://www.bethyl.com/product/A301-795A