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Rabbit anti-NUP85 Antibody, Affinity Purified

Catalog No.
A303-978A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A303-978A-M
Brand
Bethyl Laboratories
Application
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 1 and 50
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
NUP85
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
85 kDa nucleoporin, FROUNT, nuclear pore complex protein Nup85, nucleoporin 85kDa, nucleoporin Nup75, nucleoporin Nup85, Nup75, Pericentrin-1
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Rat
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Target Sentence
Nucleoporin 85 (NUP85) is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex, it plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2 and seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BW27].
Product Link
http://www.bethyl.com/product/A303-978A
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