A304-017A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 250 and 300
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- OAZ
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- early B-cell factor associated zinc finger protein, Ebfaz, hOAZ, JBTS19, NPHP14, OAZ, OLF-1/EBF associated zinc finger, olf1/EBF-associated zinc finger protein, Roaz, Smad- and Olf-interacting zinc finger protein, Zfp104, ZFP423, zinc finger protein 423
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Olf1/EBF-associated zinc finger protein (OAZ) is a transcription factor that can act as either an activator or a repressor depending on the context. OAZ plays a central role in BMP signaling and olfactory neurogenesis. It associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. OAZ also acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation. OAZ is involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Additionally, OAZ controls proliferation and differentiation of neural precursors in cerebellar vermis formation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q2M1K9].
- Product Link
- http://www.bethyl.com/product/A304-017A