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Rabbit anti-OSR1 IHC Antibody, Affinity Purified

Catalog No.
IHC-00552-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00552-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 375 and 425
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
OSR1
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
OSR1, oxidative stress-responsive 1 protein, serine/threonine-protein kinase OSR1
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.
Product Link
http://www.bethyl.com/product/IHC-00552-T
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