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Rabbit anti-p14ARF IHC Antibody, Affinity Purified

Catalog No.
IHC-00196-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00196-T
Brand
Bethyl Laboratories
Application
IHC
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 82 and C-term
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
p14ARF
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
alternative reading frame, ARF, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, cell cycle negative regulator beta, CMM2, cyclin-dependent kinase 4 inhibitor A, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), INK4, INK4A, MLM, MTS1, MTS-1, multiple tumor suppressor 1, P14, P14ARF, P16, P16INK4, p16-INK4, P16INK4A, P16-INK4A, P19, P19ARF, TP16
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Target Sentence
p14ARF regulates the cell cycle by inhibiting mdm2 and stabilizing p53 leading to inactivation of cyclin/CDK complexes. p14ARF is transcribed from an alternate open reading frame (ARF) of the CDKN2A gene. CDKN2A is frequently mutated or deleted in a wide variety of tumors and is known to be an important tumor suppressor gene. The CDKN2A gene also generates a distinct transcript variant and protein p16INK4a.
Product Link
http://www.bethyl.com/product/IHC-00196-T
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