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Rabbit anti-p57kip2 Antibody, Affinity Purified

Catalog No.
A302-347A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A302-347A-T
Brand
Bethyl Laboratories
Application
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 266 and 316
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
p57kip2
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
BWCR, BWS, cyclin-dependent kinase inhibitor 1C, cyclin-dependent kinase inhibitor 1C (p57, Kip2), cyclin-dependent kinase inhibitor p57, KIP2, p57, p57Kip2, WBS
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. A302-347A has not performed satisfactorily when used for WB of p57KIP2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of p57KIP2.
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Target Sentence
p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate [taken from NCBI GeneID:1028].
Product Link
http://www.bethyl.com/product/A302-347A
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