Rabbit anti-PABPN1 Antibody, Affinity Purified
Brand:
A303-523A-M
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1 and 50
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- PABPN1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- Nuclear poly(A)-binding protein 1, OPMD, PAB2, PABII, PABP2, PABP-2, poly(A) binding protein 2, poly(A) binding protein II, Poly(A)-binding protein 2, Poly(A)-binding protein II, Polyadenylate-binding nuclear protein 1, polyadenylate-binding protein 2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- Polyadenylate binding protein, nuclear 1 (PABPN1) is involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. PABPN1 stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. PABPN1 increases the affinity of poly(A) polymerase for RNA and is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86U42].
- Product Link
- http://www.bethyl.com/product/A303-523A
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