A301-260A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 40 and 90
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PAK1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- alpha-PAK, p21 protein (Cdc42/Rac)-activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related), p21-activated kinase 1, p65-PAK, PAK-1, PAKalpha, serine/threonine-protein kinase PAK 1, STE20 homolog, yeast
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. Use rabbit anti-PAK1 antibody A301-259A.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- PAK1 (p21-activated kinase 1) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. PAK1 mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins, Cdc42 and Rac. GTPase binding to PAK1 activates PAK1 kinase activity and leads to reorganization of the actin cytoskeleton and the phosphorylation of proteins involved in survival, energy metabolism, gene expression, cell motility, cell morphology, and the cell cycle.
- Product Link
- http://www.bethyl.com/product/A301-260A