Rabbit anti-Parafibromin Antibody, Affinity Purified
Brand:
A300-170A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 250 and 300
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- Parafibromin
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- C1orf28, cell division cycle 73 Paf1/RNA polymerase II complex component-like protein, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog, cell division cycle protein 73 homolog, FIHP, HPTJT, HRPT1, HRPT2, hyperparathyroidism 2 protein, HYX, Paf1/RNA polymerase II complex component, parafibromin
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:5,000 - 1:20,000
- Immunoprecipitation (IP)
- 1 - 4 µg/mg lysate
- Target Sentence
- Parafibromin, also known as HRPT2 (hyperparathyroidism 2 protein), has been identified as a tumor suppressor that is associated with hyperparathyroidism-jaw tumor syndrome, an autosomal dominant disease characterized by hyperparathyroidism due to parathyroid tumors and ossifying fibromas of the mandible and maxilla. Parafibromin is a component of the PAF1 complex that associates with RNA polymerase II and plays a role in mRNA 3’-end processing and transcription elongation. Parafibromin has been demonstrated to function as an inhibitor of the cell cycle.
- Product Link
- http://www.bethyl.com/product/A300-170A
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