Rabbit anti-PARD3 Antibody, Affinity Purified
Brand:
A304-496A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 1306 and 1356
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- PARD3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- ASIP, atypical PKC isotype-specific interacting protein, Atypical PKC isotype-specific-interacting protein, Baz, bazooka, CTCL tumor antigen se2-5, PAR3, PAR-3, par-3 family cell polarity regulator alpha, par-3 partitioning defective 3 homolog, PAR3alpha, PAR3-alpha, PARD-3, PARD3A, partitioning defective 3 homolog, PPP1R118, protein phosphatase 1, regulatory subunit 118, SE2-5L16, SE2-5LT1, SE2-5T2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- Partitioning defective 3 homolog (Par3) is an adapter protein involved in asymmetrical cell division and cell polarization processes. It seems to play a central role in the formation of epithelial tight junctions and targets the phosphatase PTEN to cell junctions (By similarity). Par3 association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Par3 is required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEW0].
- Product Link
- http://www.bethyl.com/product/A304-496A
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