Rabbit anti-PCSK9 Antibody, Affinity Purified
Brand:
A305-107A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and 500
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PCSK9
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- convertase subtilisin/kexin type 9 preproprotein, FH3, HCHOLA3, LDLCQ1, NARC1, NARC-1, neural apoptosis regulated convertase 1, Neural apoptosis-regulated convertase 1, PC9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, subtilisin/kexin-like protease PC9
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Monkey, Gorilla and Chimpanzee
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-107A has not performed satisfactorily when used for WB of PCSK9 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PCSK9.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- The gene PCSK9, also known as NARC1, encodes for proprotein convertase subtilisin/kexin type 9. A member of the subtilisin-like proprotein convertase family, this protein is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia [taken from NCBI Entrez Gene (Gene ID: 255738)].
- Product Link
- http://www.bethyl.com/product/A305-107A
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