A304-798A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 75 and 125
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PDCD10/CCM3
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- apoptosis-related protein 15, CCM3, cerebral cavernous malformations 3 protein, programmed cell death protein 10, TF-1 cell apoptosis-related protein 15, TFAR15
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Chicken
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A304-798A has not performed satisfactorily when used for WB of PDCD10/CCM3 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PDCD10/CCM3.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- PDCD10 is an evolutionarily conserved protein associated with cell apoptosis. PDCD10 interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent [taken from NCBI Entrez Gene (Gene ID: 11235)].
- Product Link
- http://www.bethyl.com/product/A304-798A