A305-063A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 325 and 375
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PEG10
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- EDR, embryonal carcinoma differentiation regulated, Embryonal carcinoma differentiation-regulated protein, HB-1, mammalian retrotransposon-derived 2, mammalian retrotransposon-derived protein 2, Mar2, Mart2, MEF3 like 1, MEF3L, MEF3-like protein 1, myelin expression factor 3-like protein 1, paternally expressed gene 10 protein, retrotransposon gag domain-containing protein 3, retrotransposon Gag like 2, retrotransposon-derived gag-like polyprotein, retrotransposon-derived protein PEG10, RGAG3, RTL2, SIRH1, Sushi-Ichi retrotransposon homolog 1, ty3/Gypsy-like protein
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-063A has not performed satisfactorily when used for WB of PEG10 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PEG10.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Retrotransposon-derived protein PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. PEG10 may also have a role in cell growth promotion and hepatoma formation. It inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1 [taken from UniProtKB (Entry: Q86TG7)].
- Product Link
- http://www.bethyl.com/product/A305-063A