Rabbit anti-PELP1/MNAR Antibody, Affinity Purified
Brand:
A300-876A-T
- Brand
- Bethyl Laboratories
- Application
- IHC
IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 25 and 75
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PELP1/MNAR
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- MNAR, modulator of non-genomic activity of estrogen receptor, P160, proline and glutamic acid rich nuclear protein, proline-, glutamic acid- and leucine-rich protein 1, transcription factor HMX3
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Monkey
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Immunohistochemistry (IHC)
- 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Target Sentence
- PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the “signalsome” involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
- Product Link
- http://www.bethyl.com/product/A300-876A
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