Rabbit anti-Pericentrin/Kendrin IHC Antibody, affinity purified
Brand:
IHC-00264-T
- Brand
- Bethyl Laboratories
- Application
- ICC-IF
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 175 and 225
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Pericentrin/Kendrin
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- KEN, kendrin, MOPD2, PCN, PCNT2, PCNTB, PCTN2, pericentrin, pericentrin-2, pericentrin-380, pericentrin-B, SCKL4
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunocytochemistry-Immunofluoresence (ICC-IF)
- 1:100 - 1:500
- Target Sentence
- Pericentrin (PCNT) is a large centrosomal protein that binds calmodulin and mediates assembly of the mitotic spindle apparatus. Depletion of PCNT has been shown to cause apoptosis and activation of the G2/M checkpoint. Recently, mutations in the pericentrin gene have been identified as the cause of primordial dwarfism type II (MOPDII) and Seckel syndrome. Additionally, in cells of Seckel syndrome patients, PCNT has been found to be important to the DNA damage response and ATR-dependent checkpoint signaling.
- Product Link
- http://www.bethyl.com/product/IHC-00264
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