Rabbit anti-Phospho BRCA1 (S1524) Antibody, Affinity Purified
Brand:
A300-001A-T
- Brand
- Bethyl Laboratories
- Application
- WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- surrounding serine 1524
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- BRCA1, Phospho (S1524)
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast cancer 1, early onset, breast cancer type 1 susceptibility protein, BROVCA1, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:500 - 1:5,000
- Target Sentence
- BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.
- Product Link
- http://www.bethyl.com/product/A300-001A
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