Rabbit anti-Phospho RPA32 (S33) Antibody, Affinity Purified
Brand:
A300-246A-M
- Brand
- Bethyl Laboratories
- Application
- WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- surrounding serine 33
- Buffer
- Tris-buffered Saline containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RPA32, Phospho (S33)
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- REPA2, replication factor A protein 2, replication protein A 32 kDa subunit, replication protein A 34 kDa subunit, RF-A protein 2, RP-A p32, RP-A p34, RPA32
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:1,000 - 1:5,000. Numerous bands representing proteins that migrate more slowly than 60 to 70 kDA have been observed during WB. Under some conditions, at least two of these may be more intense than the band that represents phospho RPA32-S33.
- Target Sentence
- Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA2, the 32kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.
- Product Link
- http://www.bethyl.com/product/A300-246A
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