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Rabbit anti-PKC-alpha Antibody, Affinity Purified

Catalog No.
A302-446A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (200 µg/ml)
Quantity
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Brand:
Specifications
A302-446A-M
Brand
Bethyl Laboratories
Application
IHC-IF
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 622 and 672
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
PKC-alpha
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
AAG6, aging-associated gene 6, PKCA, PKC-A, PKCalpha, PKC-alpha, PKCI+/-, PRKACA, protein kinase C alpha type
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
2 - 5 µg/mg lysate
Immunohistochemistry-Immunofluoresence (IHC-IF)
1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Sentence
Protein kinase C alpha (PKC-alpha) is a member of the PKC family of serine-threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC-alpha has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control [taken from NCBI Entrez Gene (GeneID: 5578)].
Product Link
http://www.bethyl.com/product/A302-446A
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