A302-940A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 1240 and 1290
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- PLC-gamma 1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, NCKAP3, phosphatidylinositol phospholipase C, phosphoinositidase C, phosphoinositide phospholipase C, phosphoinositide phospholipase C-gamma-1, phospholipase C, gamma 1 (formerly subtype 148), phospholipase C-148, Phospholipase C-gamma-1, phospholipase C-II, PLC1, PLC148, PLC-148, PLCgamma1, PLC-gamma-1, PLC-II, triphosphoinositide phosphodiesterase
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- PLC-gamma1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. Also, PLC-gamma1 has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase [taken from NCBI Entrez Gene (Gene ID: 5335].
- Product Link
- http://www.bethyl.com/product/A302-940A