Rabbit anti-PNP Antibody, Affinity Purified
Brand:
A304-240A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 239 and 289
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PNP
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- epididymis secretory sperm binding protein Li 156an, HEL-S-156an, inosine phosphorylase, inosine-guanosine phosphorylase, NP, PNP, PRO1837, PUNP, purine nucleoside phosphorylase, purine-nucleoside:orthophosphate ribosyltransferase
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Purine nucleoside phosphorylase (PNP) is an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The PNP enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described [taken from NCBI Entrez Gene (Gene ID: 4860)].
- Product Link
- http://www.bethyl.com/product/A304-240A
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