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Rabbit anti-PP2A Antibody, Affinity Purified

Catalog No.
A300-731A-M
Pack Size
  • 20 µl (2 blots)
  • 100 µl (10 blots)
  • 100 µl (200 µg/ml)
Quantity
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Brand:
Specifications
A300-731A-M
Brand
Bethyl Laboratories
Application
IP
WB
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 1 and 50
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human, Mouse
Target
PP2A
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
PP2Abeta, PP2A-beta, PP2CB, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isozyme, protein phosphatase 2A catalytic subunit, beta isoform, protein phosphatase type 2A catalytic subunit, serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform, serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, testicular tissue protein Li 146
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Rat
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
1:2,000 - 1:10,000
Immunoprecipitation (IP)
Not recommended. Use rabbit anti-PP2A antibody A300-732A.
Target Sentence
PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. PP2A encodes the beta isoform of the catalytic subunit (PP2CB). Chk2 has been shown to be negatively regulated and dephosphorylated by PP2A. Several proteins have been shown to associate with PP2A and regulate its activity such as eRF1, Hox11, CK2, and Igbp1/alpha4. Rapamycin has been shown to dissociate PP2A from alpha-4 and inhibit proliferation. This result suggests an alternative positive regulatory role of PP2A in cell proliferation.
Product Link
http://www.bethyl.com/product/A300-731A
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