Rabbit anti-PPAR-gamma Antibody, Affinity Purified
Brand:
A304-460A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 50 and 100
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- PPAR-gamma
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CIMT1, GLM1, NR1C3, nuclear receptor subfamily 1 group C member 3, peroxisome proliferator-activated nuclear receptor gamma variant 1, peroxisome proliferator-activated receptor gamma, PPARG1, PPARG2, PPARgamma, PPAR-gamma
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:10,000 - 1:25,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- PPAR-gamma is a nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. PPAR-gamma is a key regulator of adipocyte differentiation and glucose homeostasis and acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P37231].
- Product Link
- http://www.bethyl.com/product/A304-460A
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