Rabbit anti-PTP1B Antibody, Affinity Purified
Brand:
A302-297A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 275 and 325
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PTP1B
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- protein tyrosine phosphatase, placental, protein-tyrosine phosphatase 1B, PTP1B, PTP-1B, tyrosine-protein phosphatase non-receptor type 1
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A302-298A has not performed satisfactorily when used for WB of PTP1B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PTP1B.
- Immunoprecipitation (IP)
- 10 µg/mg lysate
- Target Sentence
- Protein-tyrosine phosphatases 1B (PTP1B) is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTP1B has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
- Product Link
- http://www.bethyl.com/product/A302-297A
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