A304-969A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 545 and 595
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- PTPN6/SHP1
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- HCP, HCPH, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, protein-tyrosine phosphatase 1C, protein-tyrosine phosphatase SHP-1, PTP-1C, SHP1, SHP-1, SHP-1L, SH-PTP1, tyrosine-protein phosphatase non-receptor type 6
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- Not recommended
- Target Sentence
- PTPN6/SHP-1 modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, SHP-1 induces UBE2V2 expression upon angiotensin II stimulation.SHP-1 plays a key role in hematopoiesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29350].
- Product Link
- http://www.bethyl.com/product/A304-969A