Rabbit anti-Pur-beta Antibody, Affinity Purified
Brand:
A303-650A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 262 and 312
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Pur-beta
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- PURBETA, Purine-rich element-binding protein B, transcriptional activator protein Pur-beta
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A303-650A has not performed satisfactorily when used for WB of Pur-beta in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Pur-beta.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Pur-beta (purine-rich element binding protein B) is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the Pur-beta gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia [taken from NCBI Entrez Gene (Gene ID: 5814)].
- Product Link
- http://www.bethyl.com/product/A303-650A
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