Rabbit anti-Rad9 IHC Antibody, Affinity Purified
Brand:
IHC-00376-T
- Brand
- Bethyl Laboratories
- Application
- IHC
IHC-IF
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- Between 350 and C-term
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human
- Target
- Rad9
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, hRAD9, RAD9, RAD9 homolog A
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Immunohistochemistry-Immunofluoresence (IHC-IF)
- 1:50 - 1:500
- Target Sentence
- Rad9 is a cell-cycle checkpoint protein with 3’-5’ exonuclease activity and is part of the 9-1-1 complex. The 9-1-1 complex, also called the checkpoint clamp, is a trimeric complex that includes Rad9, Hus1, and Rad1. This complex is recruited by the RAD17/RFC clamp loader to DNA lesions where it aids in the activation of Chk2 by ATM and ATRIP and the subsequent triggering of the checkpoint signaling cascade. In addition to its role in sensing DNA damage, Rad9 also functions in the base excision repair process of DNA repair.
- Product Link
- http://www.bethyl.com/product/IHC-00376-T
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