Rabbit anti-RAF1/c-RAF Antibody, Affinity Purified
Brand:
A301-519A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 598 and 648
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- RAF1/c-RAF
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CMD1NN, CRAF, c-Raf, C-Raf proto-oncogene, serine/threonine kinase, NS5, Oncogene RAF1, proto-oncogene c-RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, Raf-1, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Orangutan
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity.
- Product Link
- http://www.bethyl.com/product/A301-519A
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