Rabbit anti-RANK Antibody, Affinity Purified
Brand:
A303-808A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 450 and 500
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RANK
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- CD antigen CD265, CD265, FEO, LOH18CR1, loss of heterozygosity, 18, chromosomal region 1, ODFR, OFE, OPTB7, osteoclast differentiation factor receptor, OSTS, Paget disease of bone 2, PDB2, RANK, receptor activator of NF-KB, receptor activator of nuclear factor-kappa B, TRANCER, tumor necrosis factor receptor superfamily member 11A, tumor necrosis factor receptor superfamily, member 11a, NFKB activator
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- RANK (receptor activator of NF-KB) is a member of the TNF-receptor superfamily. TNF-receptor family members can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. RANK and its ligand are important regulators of the interaction between T cells and dendritic cells. RANK is also an essential mediator for osteoclast and lymph node development. Studies of the mouse counterpart suggest that this receptor directly mediates the osteoprotegerin ligand (OPGL)-induced osteoclastogenesis in osteoclast precursor cells [taken from NCBI Entrez Gene (Gene ID: 8792)].
- Product Link
- http://www.bethyl.com/product/A303-808A
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