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Rabbit anti-RAP80 IHC Antibody, Affinity Purified

Catalog No.
IHC-00461-T
Pack Size
  • 10 µl (5+ slides)
Quantity
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Brand:
Specifications
IHC-00461-T
Brand
Bethyl Laboratories
Application
IHC
IHC-IF
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
Between 650 and C-term
Buffer
Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Reactivity
Human
Target
RAP80
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
BRCA1-A complex subunit RAP80, RAP80, receptor-associated protein 80, retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1, X2HRIP110
Format
Whole IgG
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Immunohistochemistry (IHC)
1:100 - 1:500
Immunohistochemistry-Immunofluoresence (IHC-IF)
1:50 - 1:500
Target Sentence
RAP80 was first identified as a nuclear protein that interacts with the retinoid-related testis-associated receptor (RTR) and is able to inhibit the interaction of RTR with the N-CoR co-repressor. RAP80 has also been shown to interact with estrogen receptor alpha (ER-alpha) and modulate its activity. The modulation of ER-alpha activity is dependent on the ubiquitin-interacting motif (UIM) of RAP80. The UIM of RAP80 has also been demonstrated to be important for the BRCA1-dependent DNA repair response.
Product Link
http://www.bethyl.com/product/IHC-00461-T
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