Rabbit anti-RBBP6 Antibody, Affinity Purified
Brand:
A304-975A-M
- Brand
- Bethyl Laboratories
- Application
- IP
WB
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 50 and 100
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RBBP6
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- E3 ubiquitin-protein ligase RBBP6, MY038, P2P-R, p53-associated cellular protein of testis, PACT, proliferation potential-related protein, protein P2P-R, RB-binding Q-protein 1, RBQ-1, retinoblastoma binding protein 6, retinoblastoma-binding protein 6, retinoblastoma-binding Q protein 1, RING-type E3 ubiquitin transferase RBBP6, SNAMA
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- 1:2,000 - 1:10,000
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Retinoblastoma-binding protein 6 (RBBP6) is an E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). RBBP3 may play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53. It may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q7Z6E9].
- Product Link
- http://www.bethyl.com/product/A304-975A
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