A305-149A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 900 and 950
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RC3H2/MNAB
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- membrane associated DNA binding protein, membrane-associated nucleic acid-binding protein, MNAB, ring finger and CCCH-type zinc finger domain-containing protein 2, ring finger and CCCH-type zinc finger domains 2, RING finger protein 164, RING-type E3 ubiquitin transferase Roquin-2, RNF164, roquin-2
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A305-149A has not performed satisfactorily when used for WB of RC3H2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RC3H2.
- Immunoprecipitation (IP)
- 2 - 10 µg/mg lysate
- Target Sentence
- Roquin-2 is encoded by the gene RC3H2, also known as MNAB. Roquin-2 is a post-transcriptional repressor of mRNAs containing a conserved stem loop motif called the constitutive decay element (CDE). Binding to the CDE promotes mRNA deadenylation and degradation [taken from UniProtKB (Entry: Q9HBD1)].
- Product Link
- http://www.bethyl.com/product/A305-149A