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Rabbit anti-RC3H2/MNAB Antibody, Affinity Purified

Catalog No.
A305-149A-T
Pack Size
  • 100 µl (1000 µg/ml)
  • 10 µl (1000 µg/ml)
Quantity
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Brand:
Specifications
A305-149A-T
Brand
Bethyl Laboratories
Application
IP
Storage Conditions
2 - 8° C
Host
Rabbit
Conjugation
Unconjugated
Immunogen
between 900 and 950
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Reactivity
Human
Target
RC3H2/MNAB
Shelf Life
1 year from date of receipt
Antibody Type
Polyclonal
Alternate Names
membrane associated DNA binding protein, membrane-associated nucleic acid-binding protein, MNAB, ring finger and CCCH-type zinc finger domain-containing protein 2, ring finger and CCCH-type zinc finger domains 2, RING finger protein 164, RING-type E3 ubiquitin transferase Roquin-2, RNF164, roquin-2
Format
Whole IgG
Presumed Reactivity
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Product Type
Primary Antibodies
Product Sub Types
Primary Antibodies
UNSPSC
12352203
Western Blot (WB)
Not recommended. A305-149A has not performed satisfactorily when used for WB of RC3H2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RC3H2.
Immunoprecipitation (IP)
2 - 10 µg/mg lysate
Target Sentence
Roquin-2 is encoded by the gene RC3H2, also known as MNAB. Roquin-2 is a post-transcriptional repressor of mRNAs containing a conserved stem loop motif called the constitutive decay element (CDE). Binding to the CDE promotes mRNA deadenylation and degradation [taken from UniProtKB (Entry: Q9HBD1)].
Product Link
http://www.bethyl.com/product/A305-149A
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