Rabbit anti-RNF138 Antibody, Affinity Purified
Brand:
A302-994A-T
- Brand
- Bethyl Laboratories
- Application
- IP
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 195 and 245
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
- Reactivity
- Human
- Target
- RNF138
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- E3 ubiquitin-protein ligase RNF138, hNARF, HSD-4, NARF, nemo-like kinase associated ring finger protein, Nemo-like kinase-associated RING finger protein, NLK-associated RING finger protein, RING finger protein 138, ring finger protein 138, E3 ubiquitin protein ligase, RING-type E3 ubiquitin transferase RNF138, STRIN, testicular tissue protein Li 165
- Format
- Whole IgG
- Presumed Reactivity
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Western Blot (WB)
- Not recommended. A302-994A has not consistently performed satisfactorily when used for WB of RNF138 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RNF138.
- Immunoprecipitation (IP)
- 2 - 5 µg/mg lysate
- Target Sentence
- RING-finger protein 138 (RNF138) is an E3 ubiquitin ligase. Together with NLK, RNF138 is involved in the ubiquitination and degradation of TCF/LEF. RNF138 also exhibits auto-ubiquitination activity in combination with UBE2K. RNF138 may act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8WVD3].
- Product Link
- http://www.bethyl.com/product/A302-994A
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