Rabbit anti-RPA70 IHC Antibody, Affinity Purified
Brand:
IHC-00409-T
- Brand
- Bethyl Laboratories
- Application
- IHC
- Storage Conditions
- 2 - 8° C
- Host
- Rabbit
- Conjugation
- Unconjugated
- Immunogen
- between 350 and 400
- Buffer
- Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
- Reactivity
- Human, Mouse
- Target
- RPA70
- Shelf Life
- 1 year from date of receipt
- Antibody Type
- Polyclonal
- Alternate Names
- HSSB, MST075, MSTP075, REPA1, replication factor A protein 1, replication protein A 70 kDa DNA-binding subunit, replication protein A1, 70kDa, RF-A, RF-A protein 1, RP-A, RP-A p70, RPA70, single-stranded DNA-binding protein
- Format
- Whole IgG
- Product Type
- Primary Antibodies
- Product Sub Types
- Primary Antibodies
- UNSPSC
- 12352203
- Immunohistochemistry (IHC)
- 1:100 - 1:500
- Target Sentence
- Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
- Product Link
- http://www.bethyl.com/product/IHC-00409-T
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